This session will review the evolving recognition of a vomiting syndrome related to the frequent use of cannabis. Cannabinoid Hyperemesis Syndrome is characterized by chronic cannabis use, cyclic episodes of nausea and vomiting, and frequent hot bathing. While cannabis has a known anti emetic effect, the paradoxical mechanism of this syndrome remains unclear. The common factors of nausea and vomiting offers a long list of differential diagnosis with this emerging syndrome often not considered. This workshop will educate midwives on the syndrome, help identify clues for diagnosis, and overview a workup as well as provide recommendations for treatment.